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New Delhi: A new study published in the journal Covid-19 can infect a high proportion of pregnant women, and when symptomatic, a large proportion of them can develop moderate to severe disease. Indian Journal of Medical Research Thursday.
Pregnant and postpartum women under the age of 30 face twice as many severe illness as women above 30, says study, prompting immediate medical attention for Covid-positive pregnant women It is recommended to give
The study was conducted under the PregCovid Registry, a prospective prospective study of 4,203 COVID-positive pregnant and postpartum women in Maharashtra. About 40 percent of these women were recruited from the Mumbai metropolitan area.
According to the study, 3,441 women (82%) were in the age group of 18-30 years.
Out of the total, 534 women (13 per cent) had symptoms of COVID, of which 382 (72 per cent) had mild, 112 (21 per cent) had moderate and 40 (7 per cent) had severe disease.
A total of 158 (3.8 per cent) pregnant and postpartum women required intensive care, of which 96 per cent cases were due to complications related to COVID.
In the study group, 16.3 percent were born prematurely. However, the study did not conclude that premature births can be attributed to COVID.
The cohort reported six per cent pregnancy loss (delivery, miscarriage and ectopic pregnancy), significantly higher than the average pregnancy loss (1 per cent) reported from Maharashtra.
Of the 40 severe COVID cases detected in the group, 28 were women who had anemia, while one had diabetes and five had tuberculosis. Anemia was found in 50 percent of the women who tested positive for the virus.
The case fatality ratio for pregnant and postpartum women was found to be 0.8 percent – 34 of the 4,203 women under observation died during pregnancy or the postpartum period.
Concomitant diseases such as anemia, tuberculosis and diabetes were associated with maternal death.
The study looked at 3,213 live births, 77 miscarriages and 834 unmarried pregnancies. The proportion of pregnancy loss including stillbirth was six percent.
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what the study says
The study recommended case-controlled studies to establish the link between pregnancy loss and COVID. It also called for greater focus on integrated tuberculosis and COVID treatment for pregnant women in India.
“Detection of tuberculosis as a risk factor is important as India has the highest burden of tuberculosis among the general population as well as pregnant women. As previously suggested, this study further reiterates that tuberculosis and COVID Health services should be integrated for the treatment of-19, and pregnant women with respiratory symptoms should be tested for both Covid-19 and tuberculosis,” it said.
The study further advocated for vaccination of pregnant women. “With the availability of vaccines, pregnant women can be counseled for vaccination to reduce the adverse impact of COVID-19 on maternal health,” it said.
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