A recent study of the genetics of acne has identified 29 regions of the genome that affect the condition. The study was published in ‘Nature Communications’. These genetic insights offered potential new targets for treatment. They can also help physicians identify individuals at high risk of serious disease. Acne is a common skin condition. Estimates suggest that it affects up to 80 percent of adolescents. Spots and cysts, pigment changes and scarring are all common features. The face is the most common site, with the chest and back often also involved. The negative psychological consequences of acne are seen at all ages, but are perhaps of particular concern to adolescents. The study identified 29 new genetic variants that are more common in people with acne. The research also found a link between genetic risk of acne and the severity of the disease. Individuals who have the highest genetic risk are more likely to develop severe disease. While further research is needed, this finding enhances the potential for early intervention to identify individuals at risk of serious disease.
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